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SSTR2 抗体 (C-Term)

This anti-SSTR2 antibody is a 兔 多克隆 antibody detecting SSTR2 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6266273
发货至: 中国

Quick Overview for SSTR2 抗体 (C-Term) (ABIN6266273)

抗原

See all SSTR2 抗体
SSTR2 (Somatostatin Receptor 2 (SSTR2))

适用

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人, 大鼠, 小鼠

宿主

  • 44
  • 5
  • 2

克隆类型

  • 39
  • 9
  • 2
多克隆

标记

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This SSTR2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    SSTR2 Antibody detects endogenous levels of total SSTR2.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human SSTR2, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    SSTR2 (Somatostatin Receptor 2 (SSTR2))

    别名

    SSTR2

    背景

    Description: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    Gene: SSTR2

    分子量

    41kDa

    基因ID

    6752

    UniProt

    P30874
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