GLRA1 抗体 (Internal Region)
Quick Overview for GLRA1 抗体 (Internal Region) (ABIN6266217)
抗原
See all GLRA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- GLRA1 Antibody detects endogenous levels of total GLRA1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human GLRA1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Glycine Receptor, alpha 1 (GLRA1) (AA 23-113) antibody
GLRA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 121-220) antibodyGLRA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 29-154) antibodyGLRA1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 7F8E2 unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) antibodyGLRA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (Internal Region) antibodyVerified GLRA1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 121-220) antibodyGLRA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D9 unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) antibodyGLRA1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (N-Term) antibodyGLRA1 适用: 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 1-449) antibodyGLRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (Middle Region) antibodyGLRA1 适用: 人, 大鼠, 小鼠, 犬, Cow, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- GLRA1 (Glycine Receptor, alpha 1 (GLRA1))
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别名
- GLRA1
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背景
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Description: Glycine receptors are ligand-gated chloride channels (PubMed:23994010, PubMed:25730860). Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:7920629, PubMed:14551753, PubMed:16144831, PubMed:22715885, PubMed:22973015, PubMed:25973519, PubMed:9009272). Channel opening is also triggered by taurine and beta-alanine (PubMed:16144831, PubMed:9009272). Channel characteristics depend on the subunit composition, heteropentameric channels are activated by lower glycine levels and display faster desensitization (PubMed:14551753). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Channel activity is potentiated by ethanol (PubMed:25973519). Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (By similarity).
Gene: GLRA1
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分子量
- 53kDa
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基因ID
- 2741
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UniProt
- P23415
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途径
- Synaptic Membrane
抗原
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