Histone 3 抗体 (H3K27me3)
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- 抗原 See all Histone 3 (H3) 抗体
- Histone 3 (H3)
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抗原表位
- H3K27me3
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Histone 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Chromatin Immunoprecipitation (ChIP), Immunoprecipitation (IP), Immunocytochemistry (ICC)
- 特异性
- Tri-Methyl-Histone H3 (Lys27)/H3K27me3 Antibody detects endogenous levels of Tri-Methyl-Histone H3 only when methylated at Lys27.
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthetic methylated peptide derived from human Tri-Methyl-Histone H3 around the methylation site of Lys27.
- 亚型
- IgG
- Top Product
- Discover our top product H3 Primary Antibody
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- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:50-1:200, IP 1:50-1:200, CHIP 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis." in: Molecular oncology, Vol. 11, Issue 9, pp. 1225-1240, (2018) (PubMed).
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HBx-mediated decrease of AIM2 contributes to hepatocellular carcinoma metastasis." in: Molecular oncology, Vol. 11, Issue 9, pp. 1225-1240, (2018) (PubMed).
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- 抗原
- Histone 3 (H3)
- 别名
- HIST3H3 (H3 产品)
- 背景
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Description: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene: HIST3H3
- 分子量
- 15kDa
- 基因ID
- 8290
- UniProt
- Q16695
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