VRK1 抗体 (Internal Region)
Quick Overview for VRK1 抗体 (Internal Region) (ABIN6266002)
抗原
See all VRK1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- VRK1 Antibody detects endogenous levels of total VRK1.
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预测反应
- Pig,Bovine,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human VRK1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Vaccinia Related Kinase 1 (VRK1) (AA 287-396) antibody
VRK1 适用: 人 WB, ELISA, IP, IF, RNAi 宿主: 小鼠 Monoclonal 4F9 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (N-Term) antibodyVRK1 适用: 人 WB, IHC, ELISA, IP, IF 宿主: 小鼠 Monoclonal 5D1 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 257-396) antibodyVRK1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 1-396) antibodyVRK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 1-396) antibodyVRK1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) antibodyVRK1 适用: 人 WB 宿主: 小鼠 Monoclonal 5C1 unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 287-396) antibodyVRK1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Vaccinia Related Kinase 1 (VRK1) (AA 292-329), (C-Term) antibodyVRK1 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- VRK1 (Vaccinia Related Kinase 1 (VRK1))
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别名
- VRK1
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背景
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Description: Serine/threonine kinase involved in Golgi disassembly during the cell cycle: following phosphorylation by PLK3 during mitosis, required to induce Golgi fragmentation. Acts by mediating phosphorylation of downstream target protein. Phosphorylates 'Thr-18' of p53/TP53 and may thereby prevent the interaction between p53/TP53 and MDM2. Phosphorylates casein and histone H3. Phosphorylates BANF1: disrupts its ability to bind DNA, reduces its binding to LEM domain-containing proteins and causes its relocalization from the nucleus to the cytoplasm. Phosphorylates ATF2 which activates its transcriptional activity.
Gene: VRK1
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分子量
- 45 kDa
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基因ID
- 7443
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UniProt
- Q99986
抗原
-
