ULK2 抗体 (Internal Region)
Quick Overview for ULK2 抗体 (Internal Region) (ABIN6265890)
抗原
See all ULK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ULK2 Antibody detects endogenous levels of total ULK2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ULK2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Unc-51 Like Kinase 2 (ULK2) (C-Term) antibody
ULK2 适用: 人, 小鼠 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 1-155) antibodyULK2 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2H4B2 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 1-155) antibodyULK2 适用: 人, 小鼠, 大鼠 宿主: 小鼠 Monoclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 211-276) antibodyULK2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2A12 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6D12 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6C12 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 7G5 unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 930-1000) antibodyULK2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Unc-51 Like Kinase 2 (ULK2) (AA 743-843) antibodyULK2 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ULK2 (Unc-51 Like Kinase 2 (ULK2))
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别名
- ULK2
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背景
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Description: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-kinase PIK3C3 to regulate the formation of autophagophores, the precursors of autophagosomes. Part of regulatory feedback loops in autophagy: acts both as a downstream effector and a negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR. Activated via phosphorylation by AMPK, also acts as a negative regulator of AMPK through phosphorylation of the AMPK subunits PRKAA1, PRKAB2 and PRKAG1. May phosphorylate ATG13/KIAA0652, FRS2, FRS3 and RPTOR, however such data need additional evidences. Not involved in ammonia-induced autophagy or in autophagic response of cerebellar granule neurons (CGN) to low potassium concentration. Plays a role early in neuronal differentiation and is required for granule cell axon formation: may govern axon formation via Ras-like GTPase signaling and through regulation of the Rab5-mediated endocytic pathways within developing axons.
Gene: ULK2
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分子量
- 113kDa
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基因ID
- 9706
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UniProt
- Q8IYT8
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途径
- Regulation of Cell Size, Autophagy
抗原
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