RUNX2 抗体 (Internal Region)
Quick Overview for RUNX2 抗体 (Internal Region) (ABIN6264882)
抗原
See all RUNX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RUNX2 Antibody detects endogenous levels of total RUNX2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RUNX2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibody
RUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-350) antibodyRUNX2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 242-521) antibodyRUNX2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (N-Term) antibodyRUNX2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 445-474) antibodyRUNX2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人, 大鼠 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人 WB, ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1D8 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) antibodyRUNX2 适用: 人 WB, IP 宿主: 兔 Monoclonal unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (AA 251-351) antibodyRUNX2 适用: 人 WB, IF, IHC (p), EIA 宿主: 小鼠 Monoclonal 1D2 unconjugated
anti-Runt-Related Transcription Factor 2 (RUNX2) (pSer451) antibodyRUNX2 适用: 人 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RUNX2 (Runt-Related Transcription Factor 2 (RUNX2))
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别名
- RUNX2
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背景
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Description: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335, PubMed:28738062, PubMed:28703881). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
Gene: RUNX2
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分子量
- 56 kDa
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基因ID
- 860
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UniProt
- Q13950
抗原
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