MST1R 抗体 (C-Term)
Quick Overview for MST1R 抗体 (C-Term) (ABIN6264804)
抗原
See all MST1R 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- RON Antibody detects endogenous levels of total RON.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RON, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 89-275) antibody
MST1R 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (pTyr1238) antibodyMST1R 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 1092-1316) antibodyMST1R 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 210-320) antibodyMST1R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1B5A9 unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (pTyr1238), (pTyr1239) antibodyMST1R 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (pSer1394) antibodyMST1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (N-Term) antibodyMST1R 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 1175-1400) antibodyMST1R 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 600-633) antibodyMST1R 适用: 人 WB 宿主: 兔 Polyclonal RB58004 unconjugated
anti-Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R) (AA 26-125) antibodyMST1R 适用: 人 ELISA 宿主: 小鼠 Monoclonal 4E2 unconjugated
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应用备注
- WB: 1:500-1:3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MST1R (Macrophage Stimulating 1 Receptor (C-Met-Related tyrosine Kinase) (MST1R))
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别名
- MST1R
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背景
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Description: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to MST1 ligand. Regulates many physiological processes including cell survival, migration and differentiation. Ligand binding at the cell surface induces autophosphorylation of RON on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1 or the adapter GAB1. Recruitment of these downstream effectors by RON leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. RON signaling activates the wound healing response by promoting epithelial cell migration, proliferation as well as survival at the wound site. Plays also a role in the innate immune response by regulating the migration and phagocytic activity of macrophages. Alternatively, RON can also promote signals such as cell migration and proliferation in response to growth factors other than MST1 ligand.
Gene: MST1R
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分子量
- 152kDa
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基因ID
- 4486
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UniProt
- Q04912
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途径
- RTK signaling
抗原
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