PSMA7 抗体 (Internal Region)
Quick Overview for PSMA7 抗体 (Internal Region) (ABIN6264473)
抗原
See all PSMA7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- PSMA7 Antibody detects endogenous levels of total PSMA7.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PSMA7, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Proteasome Subunit alpha 7 (PSMA7) (AA 1-248) antibody
PSMA7 适用: 人 WB, ELISA, IF, IP, IHC (p) 宿主: 小鼠 Monoclonal 1A10-3G12 unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 5-232) antibodyPSMA7 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) antibodyPSMA7 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 1-248) antibodyPSMA7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 1-248) antibodyPSMA7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (Center) antibodyPSMA7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) antibodyPSMA7 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) antibodyPSMA7 适用: 人 WB, IHC, FACS 宿主: 小鼠 Monoclonal 3F11 unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 3-211) antibodyPSMA7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Proteasome Subunit alpha 7 (PSMA7) (AA 100-126) antibodyPSMA7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB21043 unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PSMA7 (Proteasome Subunit alpha 7 (PSMA7))
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别名
- PSMA7
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背景
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Description: Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
Gene: PSMA7
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分子量
- 40 kDa
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基因ID
- 5688
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UniProt
- O14818
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途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
抗原
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