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CD31 抗体 (C-Term)

Name: CD31 抗体 (C-Term)
SKU: ABIN6264129
Availability: OutOfStock

PECAM1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated

Western blot analysis of CD31 expression in mouse lung tissue lysates. (CD31 抗体 (C-Term))

Western blot analysis of PECAM-1 expression in Jurkat whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (CD31 抗体 (C-Term))

2 images

(3 references)

产品编号 ABIN6264129

发货至: 中国

Datasheet as PDF

抗原 See all CD31 (PECAM1) 抗体

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))
抗原表位
16

16

14

12

10

8

7

7

6

6

4

4

4

3

3

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
263

135

73

59

43

31

21

20

11

7

4

4

4

1

1

1
人, 小鼠, 大鼠
宿主
156

139

42

8

6

3

2
兔
Compatible Secondaries
克隆类型
221

126

8

1
多克隆
标记
155

30

30

24

13

5

5

5

5

5

5

5

5

5

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1
This CD31 antibody is un-conjugated
应用范围
229

176

103

97

59

36

35

34

30

26

18

14

13

12

9

6

3

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

特异性

CD31 Antibody detects endogenous levels of total CD31.

预测反应

Pig,Bovine,Horse,Sheep,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human CD31, corresponding to a region within C-terminal amino acids.

亚型

IgG

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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 适用: 人, 兔, Cynomolgus FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal JC-70A unconjugated

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anti-Platelet/endothelial Cell Adhesion Molecule (PECAM1) antibody
PECAM1 适用: 人, 大鼠 FACS, WB, IHC, IF, StM 宿主: 小鼠 Monoclonal C31-3 unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl and glycerol.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
Liu, Huang, Jin, Zhou, Chen, Li, Chen, Li, Yao, Li, Lan, Ye, Wang: "MicroRNA-370 inhibits the growth and metastasis of lung cancer by down-regulating epidermal growth factor receptor expression." in: Oncotarget, Vol. 8, Issue 50, pp. 88139-88151, (2018) (PubMed).

Li, Chen, Wang, Wang, Liu: "Calpain inhibition improves erectile function in diabetic mice via upregulating endothelial nitric oxide synthase expression and reducing apoptosis." in: Asian journal of andrology, Vol. 20, Issue 4, pp. 342-348, (2018) (PubMed).

Song, Hai, Wang, Zhao, Chen, Cui, Xie, Yu, Li, Wu, Li: "Realgar transforming solution suppresses angiogenesis and tumor growth by inhibiting VEGF receptor 2 signaling in vein endothelial cells." in: Archives of pharmacal research, Vol. 41, Issue 4, pp. 467-480, (2018) (PubMed).
抗原

CD31 (PECAM1) (Platelet/endothelial Cell Adhesion Molecule (PECAM1))

别名

PECAM1 (PECAM1 产品)

背景

Description: Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions (PubMed:19342684, PubMed:17580308). Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes (PubMed:19342684). Trans-homophilic interaction may play a role in endothelial cell-cell adhesion via cell junctions (PubMed:27958302). Heterophilic interaction with CD177 plays a role in transendothelial migration of neutrophils (PubMed:17580308). Homophilic ligation of PECAM1 prevents macrophage-mediated phagocytosis of neighboring viable leukocytes by transmitting a detachment signal (PubMed:12110892). Promotes macrophage-mediated phagocytosis of apoptotic leukocytes by tethering them to the phagocytic cells, PECAM1-mediated detachment signal appears to be disabled in apoptotic leukocytes (PubMed:12110892). Modulates bradykinin receptor BDKRB2 activation (PubMed:18672896). Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in endothelial cells (PubMed:18672896). Induces susceptibility to atherosclerosis (By similarity).
Gene: PECAM1

分子量

82kDa

基因ID

5175

UniProt

P16284

途径

Regulation of Actin Filament Polymerization