Patched 1 抗体 (N-Term)
Quick Overview for Patched 1 抗体 (N-Term) (ABIN6264046)
抗原
See all Patched 1 (PTCH1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Patched/PTCH1 Antibody detects endogenous levels of total Patched/PTCH1.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Patched/PTCH1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Patched 1 (PTCH1)
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别名
- PTCH1
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背景
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Description: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Gene: PTCH1
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分子量
- 160kDa
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基因ID
- 5727
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UniProt
- Q13635
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途径
- Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation
抗原
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