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Patched 1 抗体 (N-Term)

This anti-Patched 1 antibody is a 兔 多克隆 antibody detecting Patched 1 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6264046
发货至: 中国

Quick Overview for Patched 1 抗体 (N-Term) (ABIN6264046)

抗原

See all Patched 1 (PTCH1) 抗体
Patched 1 (PTCH1)

适用

  • 40
  • 27
  • 9
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
人, 小鼠

宿主

  • 37
  • 7
  • 4

克隆类型

  • 42
  • 6
多克隆

标记

  • 36
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Patched 1 antibody is un-conjugated

应用范围

  • 34
  • 23
  • 19
  • 10
  • 7
  • 6
  • 5
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    Patched/PTCH1 Antibody detects endogenous levels of total Patched/PTCH1.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human Patched/PTCH1, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Patched 1 (PTCH1)

    别名

    PTCH1

    背景

    Description: Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.

    Gene: PTCH1

    分子量

    160kDa

    基因ID

    5727

    UniProt

    Q13635

    途径

    Hedgehog Signaling, Carbohydrate Homeostasis, Tube Formation
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