OAS1 抗体 (C-Term)
Quick Overview for OAS1 抗体 (C-Term) (ABIN6263786)
抗原
See all OAS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- OAS1 Antibody detects endogenous levels of total OAS1.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human OAS1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibody
OAS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 139-358) antibodyOAS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 302-330), (C-Term) antibodyOAS1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1937 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (Middle Region) antibodyOAS1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 马, 兔, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 74-165) antibodyOAS1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C5 unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 296-395) antibodyOAS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (C-Term) antibodyOAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 324-373) antibodyOAS1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) antibodyOAS1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) antibodyOAS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
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别名
- OAS1
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背景
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Description: Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes higher oligomers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. The secreted form displays antiviral effect against vesicular stomatitis virus (VSV), herpes simplex virus type 2 (HSV-2), and encephalomyocarditis virus (EMCV) and stimulates the alternative antiviral pathway independent of RNase L.
Gene: OAS1
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分子量
- 46 kDa
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基因ID
- 4938
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UniProt
- P00973
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途径
- Hepatitis C
抗原
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