NEIL2 抗体 (Internal Region)
Quick Overview for NEIL2 抗体 (Internal Region) (ABIN6263588)
抗原
See all NEIL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- NEIL2 Antibody detects endogenous levels of total NEIL2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NEIL2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibody
NEIL2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibodyNEIL2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease 8-like 2 (NEIL2) antibodyNEIL2 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 2626C2a unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NEIL2 (Endonuclease 8-like 2 (NEIL2))
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别名
- NEIL2
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背景
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Description: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Has DNA glycosylase activity towards 5-hydroxyuracil and other oxidized derivatives of cytosine with a preference for mismatched double-stranded DNA (DNA bubbles). Has low or no DNA glycosylase activity towards thymine glycol, 2-hydroxyadenine, hypoxanthine and 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
Gene: NEIL2
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分子量
- 37 kDa
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基因ID
- 252969
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UniProt
- Q969S2
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途径
- DNA Damage Repair
抗原
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