NEIL2 抗体
Our Local Distributor
北京 101111
Quick Overview for NEIL2 抗体 (ABIN7229952)
抗原
See all NEIL2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
原理
- Rabbit Anti-NEIL2 Polyclonal Antibody
-
特异性
- The antibody detects endogenous levels of NEIL2 protein
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- Synthesized peptide derived from part region of human NEIL2 protein
-
亚型
- IgG
-
-
anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibody
NEIL2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-Endonuclease 8-like 2 (NEIL2) (Internal Region) antibodyNEIL2 适用: 人, 小鼠 WB, ELISA, ICC, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease 8-like 2 (NEIL2) (AA 1-332) antibodyNEIL2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease 8-like 2 (NEIL2) antibodyNEIL2 适用: 人 WB, DB 宿主: 小鼠 Monoclonal 2626C2a unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
-
有效期
- 12 months
-
-
- NEIL2 (Endonuclease 8-like 2 (NEIL2))
-
别名
- NEIL2
-
背景
- Endonuclease 8-like 2, DNA glycosylase/AP lyase Neil2, DNA-(apurinic or apyrimidinic site) lyase Neil2, Endonuclease VIII-like 2, Nei homolog 2, NEH2, Nei-like protein 2NEIL2 encodes a member of the Fpg/Nei family of DNA glycosylases. These glycosylases initiate the first step in base excision repair by cleaving oxidatively damaged bases and introducing a DNA strand break via their abasic site lyase activity. This enzyme is primarily associated with DNA repair during transcription and acts prefentially on cytosine-derived lesions, particularly 5-hydroxyuracil and 5-hydroxycytosine. It contains an N-terminal catalytic domain, a hinge region, and a C-terminal DNA-binding domain with helix-two-turn-helix and zinc finger motifs. This enzyme interacts with the X-ray cross complementing factor 1 scaffold protein as part of a multi-protein DNA repair complex. A pseudogene of this gene has been identified.
-
分子量
- 36kD
-
基因ID
- 252969
-
UniProt
- Q969S2
-
途径
- DNA Damage Repair
抗原
-
