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MMP14 抗体 (C-Term)

This anti-MMP14 antibody is a 兔 多克隆 antibody detecting MMP14 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6263294
发货至: 中国

Quick Overview for MMP14 抗体 (C-Term) (ABIN6263294)

抗原

See all MMP14 抗体
MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This MMP14 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    MMP14 Antibody detects endogenous levels of total MMP14.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MMP14, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))

    别名

    MMP14

    背景

    Description: Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development (By similarity). May be involved in actin cytoskeleton reorganization by cleaving PTK7 (PubMed:20837484). Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2 (PubMed:12714657). Cleaves ADGRB1 to release vasculostatin-40 which inhibits angiogenesis (PubMed:22330140).

    Gene: MMP14

    分子量

    65kDa

    基因ID

    4323

    UniProt

    P50281

    途径

    Autophagy
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