MBD2 抗体 (Internal Region)
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Quick Overview for MBD2 抗体 (Internal Region) (ABIN6263148)
抗原
See all MBD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- MBD2 Antibody detects endogenous levels of total MBD2.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human MBD2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Internal Region) antibody
Verified MBD2 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) antibodyKD Validated MBD2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 24GB460 unconjugated Recombinant Antibody
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 250-279) antibodyMBD2 适用: 人 WB, IF 宿主: 兔 Polyclonal RB41663 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (N-Term) antibodyMBD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 145-411) antibodyMBD2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 202-411) antibodyMBD2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (AA 10-228) antibodyMBD2 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1812CT625-9-45 unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) antibodyMBD2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) (Middle Region) antibodyMBD2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Methyl-CpG Binding Domain Protein 2 (MBD2) antibodyMBD2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- MBD2 (Methyl-CpG Binding Domain Protein 2 (MBD2))
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别名
- MBD2
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背景
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Description: Binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Binds hemimethylated DNA as well. Recruits histone deacetylases and DNA methyltransferases. Acts as transcriptional repressor and plays a role in gene silencing. Functions as a scaffold protein, targeting GATAD2A and GATAD2B to chromatin to promote repression. May enhance the activation of some unmethylated cAMP-responsive promoters.
Gene: MBD2
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分子量
- 43 kDa
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基因ID
- 8932
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UniProt
- Q9UBB5
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途径
- Chromatin Binding
抗原
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