ITGA5 抗体 (Internal Region)
Quick Overview for ITGA5 抗体 (Internal Region) (ABIN6262610)
抗原
See all ITGA5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Integrin alpha 5 Antibody detects endogenous levels of total Integrin alpha 5.
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预测反应
- Horse,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Integrin alpha 5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Integrin, alpha 5 (ITGA5) (AA 42-263) antibody
ITGA5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 5 (ITGA5) (AA 1021-1099) antibodyITGA5 适用: 人, 小鼠 WB, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 5 (ITGA5) antibodyITGA5 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 10F6 unconjugated
anti-Integrin, alpha 5 (ITGA5) (AA 111-253) antibodyITGA5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 6F6C1 unconjugated
anti-Integrin, alpha 5 (ITGA5) (AA 111-253) antibodyITGA5 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8D1G12 unconjugated
anti-Integrin, alpha 5 (ITGA5) (AA 220-472) antibodyITGA5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 5 (ITGA5) (Internal Region) antibodyITGA5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 5 (ITGA5) (AA 750-1000) antibodyITGA5 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Integrin, alpha 5 (ITGA5) (AA 575-602) antibodyITGA5 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB20677 unconjugated
anti-Integrin, alpha 5 (ITGA5) (AA 649-900) antibodyITGA5 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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别名
- ITGA5
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背景
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Description: Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin and fibrinogen. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). ITGA5:ITGB1 is a receptor for IL1B and binding is essential for IL1B signaling (PubMed:29030430).
Gene: ITGA5
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分子量
- 114 kDa
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基因ID
- 3678
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UniProt
- P08648
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途径
- Integrin Complex
抗原
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