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FZD7 抗体 (C-Term)

This anti-FZD7 antibody is a 兔 多克隆 antibody detecting FZD7 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6261841
发货至: 中国

Quick Overview for FZD7 抗体 (C-Term) (ABIN6261841)

抗原

See all FZD7 抗体
FZD7 (Frizzled Family Receptor 7 (FZD7))

适用

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人, 小鼠, 大鼠

宿主

  • 46
  • 5
  • 4
  • 3

克隆类型

  • 49
  • 8
多克隆

标记

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This FZD7 antibody is un-conjugated

应用范围

  • 49
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  • 8
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  • 1
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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 16
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    • 2
    • 2
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    • 2
    • 1
    • 1
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    C-Term

    特异性

    FZD7 Antibody detects endogenous levels of total FZD7.

    预测反应

    Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human FZD7, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    FZD7 (Frizzled Family Receptor 7 (FZD7))

    别名

    FZD7

    背景

    Description: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    Gene: FZD7

    分子量

    63 kDa

    基因ID

    8324

    UniProt

    O75084

    途径

    WNT signaling, Stem Cell Maintenance
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