FKBP1A 抗体 (N-Term)
Quick Overview for FKBP1A 抗体 (N-Term) (ABIN6261753)
抗原
See all FKBP1A 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- FKBP1A Antibody detects endogenous levels of total FKBP1A.
-
预测反应
- Pig,Bovine,Rabbit,Xenopus
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human FKBP1A, corresponding to a region within N-terminal amino acids.
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))
-
别名
- FKBP1A
-
背景
-
Description: Keeps in an inactive conformation TGFBR1, the TGF-beta type I serine/threonine kinase receptor, preventing TGF-beta receptor activation in absence of ligand. Recruits SMAD7 to ACVR1B which prevents the association of SMAD2 and SMAD3 with the activin receptor complex, thereby blocking the activin signal. May modulate the RYR1 calcium channel activity. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Gene: FKBP1A
-
分子量
- 12kDa
-
基因ID
- 2280
-
UniProt
- P62942
-
途径
- Negative Regulation of Transporter Activity, Methionine Biosynthetic Process
抗原
-