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ERBB3 抗体 (C-Term)

This anti-ERBB3 antibody is a 兔 多克隆 antibody detecting ERBB3 in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6261585
发货至: 中国

Quick Overview for ERBB3 抗体 (C-Term) (ABIN6261585)

抗原

See all ERBB3 抗体
ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ERBB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
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    C-Term

    特异性

    HER3/ErbB3 Antibody detects endogenous levels of total ERBB3.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ERBB3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

    别名

    ERBB3

    背景

    Description: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134).

    Gene: ERBB3

    分子量

    148kDa

    基因ID

    2065

    UniProt

    P21860

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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