Ephrin A5 抗体 (Internal Region)
Quick Overview for Ephrin A5 抗体 (Internal Region) (ABIN6261451)
抗原
See all Ephrin A5 (EFNA5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- Ephrin A5 Antibody detects endogenous levels of total Ephrin A5.
-
预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human Ephrin A5, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Ephrin A5 (EFNA5) (AA 114-203) antibody
EFNA5 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-Ephrin A5 (EFNA5) (AA 114-203) antibodyEFNA5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (AA 21-203) antibodyEFNA5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Center) antibodyEFNA5 适用: 人, 大鼠, 小鼠, Cow, 兔, 小鸡 WB, IHC, IF, FACS, IC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (AA 31-80) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (AA 172-186), (Extracellular) antibodyEFNA5 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (C-Term) antibodyEFNA5 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (C-Term) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Internal Region) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- Ephrin A5 (EFNA5)
-
别名
- EFNA5
-
背景
-
Description: Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Induces compartmentalized signaling within a caveolae-like membrane microdomain when bound to the extracellular domain of its cognate receptor. This signaling event requires the activity of the Fyn tyrosine kinase. Activates the EPHA3 receptor to regulate cell-cell adhesion and cytoskeletal organization. With the receptor EPHA2 may regulate lens fiber cells shape and interactions and be important for lens transparency maintenance. May function actively to stimulate axon fasciculation. The interaction of EFNA5 with EPHA5 also mediates communication between pancreatic islet cells to regulate glucose-stimulated insulin secretion. Cognate/functional ligand for EPHA7, their interaction regulates brain development modulating cell-cell adhesion and repulsion.
Gene: EFNA5
-
分子量
- 25kDa
-
基因ID
- 1946
-
UniProt
- P52803
-
途径
- RTK signaling
抗原
-
