Ephrin A5 抗体 (Extracellular)
Our Local Distributor
北京 101111
Quick Overview for Ephrin A5 抗体 (Extracellular) (ABIN7043130)
抗原
See all Ephrin A5 (EFNA5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 172-186, Extracellular
-
原理
- A Rabbit Polyclonal Antibody to Ephrin A5
-
交叉反应
- 人, 小鼠, 大鼠
-
预测反应
- Mouse,rat - identical
-
产品特性
- Anti-Ephrin-A5 (extracellular) Antibody (ABIN7043130, ABIN7044259 and ABIN7044260) is a highly specific antibody directed against an epitope of human EFNA5. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize EFNA5 from rat, mouse, and human samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)DRVFDVNDKVENSLE, corresponding to amino acid residues 172-186 of human Ephrin-A5
-
亚型
- IgG
-
-
anti-Ephrin A5 (EFNA5) (AA 114-203) antibody
EFNA5 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1F12 unconjugated
anti-Ephrin A5 (EFNA5) (AA 114-203) antibodyEFNA5 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Internal Region) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (AA 21-203) antibodyEFNA5 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (AA 31-80) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Center) antibodyEFNA5 适用: 人, 大鼠, 小鼠, Cow, 兔, 小鸡 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (C-Term) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (C-Term) antibodyEFNA5 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Ephrin A5 (EFNA5) (Internal Region) antibodyEFNA5 适用: 人, 大鼠, 小鼠 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:200
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: (ABIN7235310)
Blocking Peptide: (ABIN7235310)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
-
浓度
- 0.8 mg/mL
-
缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- Ephrin A5 (EFNA5)
-
别名
- EFNA5
-
背景
-
Synonyms: EPH-related receptor tyrosine kinase ligand 7, LERK7, AL-1, EFNA5
Description: The Eph family of tyrosine kinase receptor signaling pathway is important for a variety of physiological processes during development including cell morphology, proliferation, migration and axonal guidance, dendritic spine formation and neural plasticity. Eph receptors mediate forward signaling in one cell while ephrin ligands transmit reverse signaling in an adjacent cell1-3.Eph receptors consist of two large subfamilies: EphA and EphB that bind to either glycophosphatidylinositol (GPI)-anchored ephrin-A ligands or transmembrane ephrin-B ligands respectively. Ephrin ligands are divided into ephrin-A (1 to 5) and ephrin-B (1 to 3)1,2.Ephrin-A5 is predominantly expressed in the quiescent anterior lens epithelial cells and is highly expressed in different layers of the cortex2,3.Studies show that mutations in ephrin-A5 are linked to congenital and age-related cataracts in humans and mice. Loss of ephrin-A5 causes abnormal localization of E-cadherin and β-catenin in anterior epithelial cells and epithelial-mesenchymal-transition2.
-
基因ID
- 1946
-
NCBI登录号
- NM_001962
-
UniProt
- P52803
-
途径
- RTK signaling
抗原
-
