Claudin 1 抗体 (C-Term)
Quick Overview for Claudin 1 抗体 (C-Term) (ABIN6260877)
抗原
See all Claudin 1 (CLDN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- Claudin 1 Antibody detects endogenous levels of total Claudin 1.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human Claudin 1, corresponding to a region within C-terminal amino acids.
-
亚型
- IgG
-
-
anti-Claudin 1 (CLDN1) (AA 1-211) antibody
CLDN1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1C5-D9 unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 2E2-H5 unconjugated
anti-Claudin 1 (CLDN1) (AA 121-211) antibodyCLDN1 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (p), FACS, IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 50-197) antibodyCLDN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 1-212) antibodyCLDN1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1C5-D9 unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 185-224) antibodyCLDN1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (Tyr210) antibodyCLDN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 24-161) antibodyCLDN1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Claudin 1 (CLDN1) (AA 1-211) antibodyCLDN1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- Claudin 1 (CLDN1)
-
别名
- CLDN1
-
背景
-
Description: Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members play essential roles in the formation of impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN1 is required to prevent the paracellular diffusion of small molecules through tight junctions in the epidermis and is required for the normal barrier function of the skin. Required for normal water homeostasis and to prevent excessive water loss through the skin, probably via an indirect effect on the expression levels of other proteins, since CLDN1 itself seems to be dispensable for water barrier formation in keratinocyte tight junctions (PubMed:23407391).
Gene: CLDN1
-
分子量
- 23kDa
-
基因ID
- 9076
-
UniProt
- O95832
-
途径
- Cell-Cell Junction Organization, Hepatitis C
抗原
-
