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CD28 抗体 (C-Term)

This anti-CD28 antibody is a 兔 多克隆 antibody detecting CD28 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6260603
发货至: 中国

Quick Overview for CD28 抗体 (C-Term) (ABIN6260603)

抗原

See all CD28 抗体
CD28

适用

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人, 小鼠, 大鼠

宿主

  • 139
  • 82
  • 27
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  • 2
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  • 1

克隆类型

  • 195
  • 73
  • 4
多克隆

标记

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This CD28 antibody is un-conjugated

应用范围

  • 204
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 15
    • 8
    • 5
    • 5
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    • 3
    • 3
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    C-Term

    特异性

    CD28 Antibody detects endogenous levels of total CD28.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CD28, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol. .

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CD28

    别名

    CD28

    背景

    Description: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037).

    Gene: CD28

    分子量

    25 kDa

    基因ID

    940

    UniProt

    P10747

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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