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JUP 抗体 (C-Term)

This anti-JUP antibody is a 兔 多克隆 antibody detecting JUP in WB, IF, IHC, ELISA 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6260497
发货至: 中国

Quick Overview for JUP 抗体 (C-Term) (ABIN6260497)

抗原

See all JUP 抗体
JUP (Junction Plakoglobin (JUP))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This JUP antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    Catenin gamma Antibody detects endogenous levels of total Catenin gamma.

    预测反应

    Pig,Bovine,Sheep,Rabbit,Dog,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human Catenin gamma, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    JUP (Junction Plakoglobin (JUP))

    别名

    JUP

    背景

    Description: Common junctional plaque protein. The membrane-associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE-cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton (By similarity).

    Gene: JUP

    分子量

    80 kDa

    基因ID

    3728

    UniProt

    P14923

    途径

    Cell-Cell Junction Organization, Maintenance of Protein Location
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