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CaMK2 alpha/delta 抗体

适用: 人, 小鼠, 大鼠 IF, IHC, WB, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260427
发货至: 中国
  • 抗原 See all CaMK2 alpha/delta products
    CaMK2 alpha/delta
    适用
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 3
    克隆类型
    • 3
    多克隆
    标记
    • 3
    This CaMK2 alpha/delta antibody is un-conjugated
    应用范围
    Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunocytochemistry (ICC)
    特异性
    CaMK2 alpha/delta Antibody detects endogenous levels of total CaMK2 alpha/delta
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CaMK2 alpha/delta
    亚型
    IgG
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • Cao, Xiao, Wang, Weng, Ding, Zhu, Lu: "Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." in: Neurochemical research, (2018) (PubMed).

  • 抗原
    CaMK2 alpha/delta
    Abstract
    CaMK2 alpha/delta 产品
    背景

    Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).

    Gene: CAMK2A

    分子量
    50kDa
    基因ID
    815
    UniProt
    Q9UQM7, Q13557
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