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CEBPB 抗体 (Internal Region)

Name: CEBPB 抗体 (Internal Region)
SKU: ABIN6260349
Availability: OutOfStock

This anti-CEBPB antibody is a 兔多克隆 antibody detecting CEBPB in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠和大鼠.

Western blot analysis of C/EBP-beta expression in NIH-3T3 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (CEBPB 抗体 (Internal Region))

IF/ICC

ABIN6269173 at 1/100 staining Mouse spleen tissue by IHC-P. (CEBPB 抗体 (Internal Region))

IHC

Western blot analysis of extracts from HepG2, using C/EBP-beta Antibody. (CEBPB 抗体 (Internal Region))

4 images

产品编号 ABIN6260349

发货至: 中国

Datasheet as PDF

Quick Overview for CEBPB 抗体 (Internal Region) (ABIN6260349)

抗原

See all CEBPB 抗体

CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This CEBPB antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Discover our top product CEBPB Primary Antibody

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Internal Region

特异性

CEBP Beta Antibody detects endogenous levels of total CEBP Beta.

预测反应

Pig,Bovine,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human CEBP Beta, corresponding to a region within the internal amino acids.

亚型

IgG
anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (N-Term) antibody
KO Validated CEBPB 适用: 人 WB, IHC, IP, IHC (p), IF, ICC, ChIP 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (pThr235) antibody
CEBPB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 150-250) antibody
CEBPB 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) antibody
CEBPB 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3H9 unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 271-298) antibody
CEBPB 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 68-81) antibody
Verified CEBPB 适用: 人, 小鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 271-298), (C-Term) antibody
CEBPB 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20651 unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (pSer235) antibody
CEBPB 适用: 人, 小鼠, 大鼠, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (AA 201-250), (pThr235) antibody
CEBPB 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) (pThr235) antibody
CEBPB 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

别名

CEBPB

背景

Description: Important transcription factor regulating the expression of genes involved in immune and inflammatory responses (PubMed:1741402, PubMed:9374525, PubMed:12048245, PubMed:18647749). Plays also a significant role in adipogenesis, as well as in the gluconeogenic pathway, liver regeneration, and hematopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Its functional capacity is governed by protein interactions and post-translational protein modifications. During early embryogenesis, plays essential and redundant functions with CEBPA. Has a promitotic effect on many cell types such as hepatocytes and adipocytes but has an antiproliferative effect on T-cells by repressing MYC expression, facilitating differentiation along the T-helper 2 lineage. Binds to regulatory regions of several acute-phase and cytokines genes and plays a role in the regulation of acute-phase reaction and inflammation. Plays also a role in intracellular bacteria killing (By similarity). During adipogenesis, is rapidly expressed and, after activation by phosphorylation, induces CEBPA and PPARG, which turn on the series of adipocyte genes that give rise to the adipocyte phenotype. The delayed transactivation of the CEBPA and PPARG genes by CEBPB appears necessary to allow mitotic clonal expansion and thereby progression of terminal differentiation (PubMed:20829347). Essential for female reproduction because of a critical role in ovarian follicle development (By similarity). Restricts osteoclastogenesis: together with NFE2L1, represses expression of DSPP during odontoblast differentiation (By similarity).
Gene: CEBPB

分子量

36kDa

基因ID

1051

UniProt

P17676

途径

Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation