BNIP3L/NIX 抗体 (Internal Region)
Quick Overview for BNIP3L/NIX 抗体 (Internal Region) (ABIN6260297)
抗原
See all BNIP3L/NIX (BNIP3L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- BNIP3L Antibody detects endogenous levels of total BNIP3L.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human BNIP3L, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 43-130) antibody
BNIP3L 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G2 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) antibodyBNIP3L 适用: 人, 小鼠, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) antibodyBNIP3L 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 43-130) antibodyBNIP3L 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2E11 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1H10B3 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 52-81) antibodyBNIP3L 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB19646 unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 59-89), (Middle Region) antibodyBNIP3L 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 51-150) antibodyBNIP3L 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (AA 1-187) antibodyBNIP3L 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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别名
- BNIP3L
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背景
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Description: Induces apoptosis. Interacts with viral and cellular anti-apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. May function as a tumor suppressor.
Gene: BNIP3L
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分子量
- 35 kDa
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基因ID
- 665
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UniProt
- O60238
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途径
- Autophagy
抗原
-
