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BNIP3 抗体 (C-Term)

This 兔 多克隆 anti-BNIP3 antibody specifically detects BNIP3 in WB 和 ELISA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6260296
发货至: 中国
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Quick Overview for BNIP3 抗体 (C-Term) (ABIN6260296)

抗原

See all BNIP3 抗体
BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

适用

人, 小鼠, 大鼠

宿主

  • 95
  • 9
  • 7

克隆类型

  • 74
  • 37
多克隆

标记

  • 37
  • 7
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This BNIP3 antibody is un-conjugated

应用范围

  • 66
  • 30
  • 26
  • 26
  • 22
  • 18
  • 13
  • 9
  • 8
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 15
    • 15
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    BNIP3 Antibody detects endogenous levels of total BNIP3.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human BNIP3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    BNIP3 (BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))

    别名

    BNIP3

    背景

    Description: Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP3L/NIX at the mitochondrial outer membrane regulates the opening of a pore in the mitochondrial double membrane in order to mediate the translocation of lysosomal proteins from the cytoplasm to the mitochondrial matrix. Plays an important role in the calprotectin (S100A8/A9)-induced cell death pathway.

    Gene: BNIP3

    分子量

    30 kDa

    基因ID

    664

    UniProt

    Q12983

    途径

    Autophagy, Brown Fat Cell Differentiation
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