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ATG3 抗体 (N-Term)

This anti-ATG3 antibody is a 兔多克隆 antibody detecting ATG3 in WB 和 ELISA. Suitable for 人.

Western blot analysis of ATG3 using LOVO whole cell lysates (ATG3 抗体 (N-Term))

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产品编号 ABIN6260103

发货至: 中国

Quick Overview for ATG3 抗体 (N-Term) (ABIN6260103)

抗原

See all ATG3 抗体

ATG3 (ATG3 Autophagy Related 3 (ATG3))

适用

88
41
39
7
7
4
4
4
3
2
1
1
1
1
1

人

宿主

兔

克隆类型

多克隆

标记

44
8
7
6
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2

This ATG3 antibody is un-conjugated

应用范围

73
42
26
26
17
11
10
10
7
6
4
1
1

Western Blotting (WB), ELISA

Discover our top product ATG3 Primary Antibody

抗原表位
15

15

7

6

5

4

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

特异性

ATG3 Antibody detects endogenous levels of total ATG3.

预测反应

Pig,Bovine,Sheep,Rabbit,Dog,Chicken,Xenopus

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human ATG3, corresponding to a region within N-terminal amino acids.

亚型

IgG
anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibody
ATG3 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2C10A12 unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibody
ATG3 适用: 人, 猴 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 7A1D1 unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) antibody
ATG3 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 7C2 unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-314) antibody
ATG3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) antibody
ATG3 适用: 人, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3C6 unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) antibody
ATG3 适用: 人, 大鼠, 犬, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 3G3 unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) (Middle Region) antibody
ATG3 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibody
ATG3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1G3 unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) (AA 51-150) antibody
ATG3 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-ATG3 Autophagy Related 3 (ATG3) (AA 1-100) antibody
ATG3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated

应用备注

WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

ATG3 (ATG3 Autophagy Related 3 (ATG3))

别名

ATG3

背景

Description: E2 conjugating enzyme required for the cytoplasm to vacuole transport (Cvt), autophagy, and mitochondrial homeostasis. Responsible for the E2-like covalent binding of phosphatidylethanolamine to the C-terminal Gly of ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). The ATG12-ATG5 conjugate plays a role of an E3 and promotes the transfer of ATG8-like proteins from ATG3 to phosphatidylethanolamine (PE). This step is required for the membrane association of ATG8-like proteins. The formation of the ATG8-phosphatidylethanolamine conjugates is essential for autophagy and for the cytoplasm to vacuole transport (Cvt). Preferred substrate is MAP1LC3A. Also acts as an autocatalytic E2-like enzyme, catalyzing the conjugation of ATG12 to itself, ATG12 conjugation to ATG3 playing a role in mitochondrial homeostasis but not in autophagy. ATG7 (E1-like enzyme) facilitates this reaction by forming an E1-E2 complex with ATG3. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
Gene: ATG3

分子量

40 kDa

基因ID

64422

UniProt

Q9NT62

途径

Autophagy

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