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APLF 抗体 (Internal Region)

This anti-APLF antibody is a 兔 多克隆 antibody detecting APLF in ELISA, WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6259979
发货至: 中国

Quick Overview for APLF 抗体 (Internal Region) (ABIN6259979)

抗原

See all APLF 抗体
APLF (Aprataxin and PNKP Like Factor (APLF))

适用

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人, 小鼠, 大鼠

宿主

  • 32

克隆类型

  • 32
多克隆

标记

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This APLF antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Internal Region

    特异性

    APLF Antibody detects endogenous levels of total APLF.

    预测反应

    Pig,Bovine,Horse,Sheep,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human APLF, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000, IHC: 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    APLF (Aprataxin and PNKP Like Factor (APLF))

    别名

    APLF

    背景

    Description: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.

    Gene: APLF

    分子量

    57kDa

    基因ID

    200558

    UniProt

    Q8IW19

    途径

    DNA Damage Repair
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