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APLF 抗体 (Ser116)

APLF 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7179974
发货至: 中国
  • 抗原 See all APLF 抗体
    APLF (Aprataxin and PNKP Like Factor (APLF))
    抗原表位
    • 15
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser116
    适用
    • 36
    • 17
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    克隆类型
    • 36
    多克隆
    标记
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APLF antibody is un-conjugated
    应用范围
    • 26
    • 13
    • 13
    • 13
    • 8
    • 5
    • 3
    • 1
    ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    免疫原
    Synthesized non-phosphopeptide derived from Human APLF around the phosphorylation site of serine 116 (R-N-S(p)-Q-V).
    亚型
    IgG
    Top Product
    Discover our top product APLF Primary Antibody
  • 应用备注
    WB:1:500-1:3000, IHC:1:50-1:100,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    APLF (Aprataxin and PNKP Like Factor (APLF))
    别名
    APLF (APLF 产品)
    别名
    apfl antibody, palf antibody, xip1 antibody, APLF antibody, C2orf13 antibody, DKFZp459J1223 antibody, APFL antibody, PALF antibody, Xip1 antibody, 2010301N04Rik antibody, AI452191 antibody, RGD1565557 antibody, aprataxin and PNKP like factor antibody, APLF antibody, aplf antibody, Aplf antibody
    背景

    Background: Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.

    Saunders W.S., J. Cell Sci. 104:573-582(1993).
    Ye Q., J. Biol. Chem. 271:14653-14656(1996).
    Ye Q., J. Biol. Chem. 272:14983-14989(1997).

    Aliases: 2010301N04Rik antibody, AI452191 antibody, Aplf antibody, APLF_HUMAN antibody, Aprataxin and PNK-like factor antibody, Apurinic-apyrimidinic endonuclease APLF antibody, C2orf13 antibody, PNK and APTX like FHA protein antibody, PNK and APTX-like FHA domain-containing protein antibody, RGD1565557 antibody, XIP1 antibody, XRCC1 interacting protein 1 antibody, XRCC1-interacting protein 1 antibody

    UniProt
    Q8IW19
    途径
    DNA Damage Repair
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