Angiopoietin 2 抗体 (N-Term)
Quick Overview for Angiopoietin 2 抗体 (N-Term) (ABIN6259925)
抗原
See all Angiopoietin 2 (ANGPT2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Angiopoietin 2 Antibody detects endogenous levels of total Angiopoietin 2.
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预测反应
- Pig
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Angiopoietin 2, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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: "[Dose and timing of normal saline resuscitation on endothelial glycocalyx in early septic shock]." in: Zhonghua wei zhong bing ji jiu yi xue, Vol. 30, Issue 7, pp. 629-634, (2018) (PubMed).
: "Electroacupuncture facilitates implantation by enhancing endometrial angiogenesis in a rat model of ovarian hyperstimulation." in: Biology of reproduction, (2018) (PubMed).
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: "[Dose and timing of normal saline resuscitation on endothelial glycocalyx in early septic shock]." in: Zhonghua wei zhong bing ji jiu yi xue, Vol. 30, Issue 7, pp. 629-634, (2018) (PubMed).
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- Angiopoietin 2 (ANGPT2)
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别名
- ANGPT2
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背景
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Description: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Gene: ANGPT2
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分子量
- 57 kDa
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基因ID
- 285
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UniProt
- O15123
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途径
- RTK signaling
抗原
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