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alpha 2 Macroglobulin 抗体 (Internal Region)

The 兔 多克隆 anti-alpha 2 Macroglobulin antibody (ABIN6259666) specifically detects alpha 2 Macroglobulin in WB 和 ELISA. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN6259666
发货至: 中国
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Quick Overview for alpha 2 Macroglobulin 抗体 (Internal Region) (ABIN6259666)

抗原

See all alpha 2 Macroglobulin (A2M) 抗体
alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

适用

  • 109
  • 21
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  • 5
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  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠, 小鼠

宿主

  • 105
  • 19
  • 16
  • 5
  • 2
  • 1

克隆类型

  • 112
  • 34
多克隆

标记

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This alpha 2 Macroglobulin antibody is un-conjugated

应用范围

  • 93
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  • 22
  • 11
  • 9
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  • 1
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Western Blotting (WB), ELISA
  • 抗原表位

    • 9
    • 8
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    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    Alpha 2 Macroglobulin/A2M Antibody detects endogenous levels of total alpha 2 Macroglobulin/A2M.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human alpha 2 Macroglobulin/A2M, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

    别名

    A2M

    背景

    Description: Is able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced). Following cleavage in the bait region, a thioester bond is hydrolyzed and mediates the covalent binding of the protein to the proteinase.

    Gene: A2M

    分子量

    180 kDa

    基因ID

    2

    UniProt

    P01023

    途径

    Lipid Metabolism
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