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Manic Fringe 抗体 (Internal Region)

This anti-Manic Fringe antibody is a 兔 多克隆 antibody detecting Manic Fringe in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258883
发货至: 中国

Quick Overview for Manic Fringe 抗体 (Internal Region) (ABIN6258883)

抗原

See all Manic Fringe (MFNG) 抗体
Manic Fringe (MFNG) (MFNG)

适用

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人, 小鼠, 大鼠

宿主

  • 46
  • 4
  • 1

克隆类型

  • 50
  • 1
多克隆

标记

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This Manic Fringe antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    Internal Region

    特异性

    MFNG Antibody detects endogenous levels of total MFNG.

    预测反应

    Pig,Bovine,Horse,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MFNG, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Manic Fringe (MFNG) (MFNG)

    别名

    MFNG

    背景

    Description: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity).

    Gene: MFNG

    分子量

    38 kDa

    基因ID

    4242

    UniProt

    O00587

    途径

    Notch Signaling
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