Manic Fringe 抗体 (Internal Region)
Quick Overview for Manic Fringe 抗体 (Internal Region) (ABIN6258883)
抗原
See all Manic Fringe (MFNG) 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- Internal Region
- 
                                            特异性
- MFNG Antibody detects endogenous levels of total MFNG.
- 
                                            预测反应
- Pig,Bovine,Horse,Dog
- 
                                            纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 
                                            免疫原
- A synthesized peptide derived from human MFNG, corresponding to a region within the internal amino acids.
- 
                                            亚型
- IgG
 
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    - 
                                            应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 
                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 
                                            有效期
- 12 months
 
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    - Manic Fringe (MFNG) (MFNG)
- 
                                            别名
- MFNG
- 
                                            背景
- 
                        Description: Glycosyltransferase that initiates the elongation of O-linked fucose residues attached to EGF-like repeats in the extracellular domain of Notch molecules (PubMed:10935626). Modulates NOTCH1 activity by modifying O-fucose residues at specific EGF-like domains resulting in inhibition of NOTCH1 activation by JAG1 and enhancement of NOTCH1 activation by DLL1 via an increase in its binding to DLL1 (By similarity). Gene: MFNG 
- 
                                            分子量
- 38 kDa
- 
                                            基因ID
- 4242
- 
                                            UniProt
- O00587
- 
                                            途径
- Notch Signaling
 抗原
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