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TCF7 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects TCF7 in WB, IHC, IF 和 ICC. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN6258455
发货至: 中国
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Quick Overview for TCF7 抗体 (N-Term) (ABIN6258455)

抗原

See all TCF7 抗体
TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

适用

  • 74
  • 52
  • 19
  • 7
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 64
  • 12
  • 1
兔

克隆类型

  • 63
  • 14
多克隆

标记

  • 45
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This TCF7 antibody is un-conjugated

应用范围

  • 44
  • 21
  • 20
  • 9
  • 7
  • 5
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 12
    • 11
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    原理

    TCF7 Antibody

    特异性

    TCF7 Antibody detects endogenous levels of total TCF7

    预测反应

    Pig,Bovine,Dog

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human TCF7, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    TCF7 (Transcription Factor 7 (T-Cell Specific, HMG-Box) (TCF7))

    别名

    TCF7

    背景

    Description: Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4+ CD8+ immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. May also act as feedback transcriptional repressor of CTNNB1 and TCF7L2 target genes. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7 and CTNNB1.

    Gene: TCF7

    分子量

    42 kDa

    基因ID

    6932

    UniProt

    P36402

    途径

    WNT signaling
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