NEIL1 抗体 (Internal Region)
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北京 101111
Quick Overview for NEIL1 抗体 (Internal Region) (ABIN6258289)
抗原
See all NEIL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- NEIL1 Antibody detects endogenous levels of total NEIL1.
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预测反应
- Horse,Sheep
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human NEIL1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Endonuclease VIII-Like 1 (NEIL1) antibody
NEIL1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 43-314) antibodyNEIL1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 187-476) antibodyNEIL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (C-Term) antibodyNEIL1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 2-390) antibodyNEIL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (C-Term) antibodyVerified NEIL1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 1-390) antibodyNEIL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Endonuclease VIII-Like 1 (NEIL1) (AA 1-390) antibodyNEIL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
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别名
- NEIL1
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背景
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Description: Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. Has marginal activity towards 8-oxoguanine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Has DNA glycosylase/lyase activity towards mismatched uracil and thymine, in particular in U:C and T:C mismatches. Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC.
Gene: NEIL1
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分子量
- 44 kDa
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基因ID
- 79661
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UniProt
- Q96FI4
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途径
- DNA Damage Repair
抗原
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