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NEIL1 抗体

NEIL1 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7073820
发货至: 中国
  • 抗原 See all NEIL1 抗体
    NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
    适用
    • 34
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 29
    • 4
    • 1
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NEIL1 antibody is un-conjugated
    应用范围
    • 22
    • 12
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    人, 大鼠
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse NEIL1
  • 应用备注
    WB (M,R) 1:800-1:1600, IHC/IF (H,M,R) 1:1200-1:3000/1:300-1:600
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS, pH 7.4, 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    NEIL1 (Endonuclease VIII-Like 1 (NEIL1))
    别名
    NEIL1 (NEIL1 产品)
    别名
    FPG1 antibody, NEI1 antibody, hFPG1 antibody, 2810450N13Rik antibody, Nei1 antibody, nei-like DNA glycosylase 1 antibody, nei like DNA glycosylase 1 antibody, nei endonuclease VIII-like 1 (E. coli) antibody, Neil1 antibody, NEIL1 antibody
    背景
    NEIL1, also named as NEH1 and FPG1, belongs to the FPG family. It is involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. NEIL1 acts as DNA glycosylase that recognizes and removes damaged bases. It has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. NEIL1 has marginal activity towards 8-oxoguanine. It has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.
    分子量
    44 kDa
    基因ID
    72774
    NCBI登录号
    NP_082623
    UniProt
    Q8K4Q6
    途径
    DNA Damage Repair
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