Exonuclease 1 抗体 (N-Term)
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Quick Overview for Exonuclease 1 抗体 (N-Term) (ABIN6257905)
抗原
See all Exonuclease 1 (EXO1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- EXO1 Antibody detects endogenous levels of total EXO1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human EXO1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Exonuclease 1 (EXO1) (AA 301-600) antibody
EXO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 747-846) antibodyEXO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 31-130) antibodyEXO1 适用: 人, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (Internal Region) antibodyVerified EXO1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人, 小鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Exonuclease 1 (EXO1)
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别名
- EXO1
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背景
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Description: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Gene: EXO1
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分子量
- 94 kDa
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基因ID
- 9156
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UniProt
- Q9UQ84
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途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
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