Exonuclease 1 抗体 (N-Term)
Quick Overview for Exonuclease 1 抗体 (N-Term) (ABIN6257905)
抗原
See all Exonuclease 1 (EXO1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- EXO1 Antibody detects endogenous levels of total EXO1.
-
预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human EXO1, corresponding to a region within N-terminal amino acids.
-
亚型
- IgG
-
-
anti-Exonuclease 1 (EXO1) (AA 301-600) antibody
EXO1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 601-846) antibodyEXO1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-250) antibodyEXO1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 747-846) antibodyEXO1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated
anti-Exonuclease 1 (EXO1) (AA 31-130) antibodyEXO1 适用: 人, 小鼠 WB, ELISA, ICC, FACS, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (N-Term) antibodyEXO1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Exonuclease 1 (EXO1) (AA 1-846) antibodyEXO1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- Exonuclease 1 (EXO1)
-
别名
- EXO1
-
背景
-
Description: 5'->3' double-stranded DNA exonuclease which may also possess a cryptic 3'->5' double-stranded DNA exonuclease activity. Functions in DNA mismatch repair (MMR) to excise mismatch-containing DNA tracts directed by strand breaks located either 5' or 3' to the mismatch. Also exhibits endonuclease activity against 5'-overhanging flap structures similar to those generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Required for somatic hypermutation (SHM) and class switch recombination (CSR) of immunoglobulin genes. Essential for male and female meiosis.
Gene: EXO1
-
分子量
- 94 kDa
-
基因ID
- 9156
-
UniProt
- Q9UQ84
-
途径
- DNA Damage Repair, Production of Molecular Mediator of Immune Response
抗原
-
