Septin 2 抗体 (Internal Region)
Quick Overview for Septin 2 抗体 (Internal Region) (ABIN6257343)
抗原
See all Septin 2 (SEPT2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- SEPT2 Antibody detects endogenous levels of total SEPT2.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SEPT2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Septin 2 (SEPT2) (N-Term) antibody
Verified SEPT2 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 1-361) antibodySEPT2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 1-361) antibodySEPT2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 2 (SEPT2) antibodySEPT2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 112-361) antibodySEPT2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Septin 2 (SEPT2) antibodySEPT2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Septin 2 (SEPT2) (N-Term) antibodySEPT2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, Pig, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Septin 2 (SEPT2) (N-Term) antibodySEPT2 适用: 人, 小鼠, 大鼠, 兔, 犬, Pig, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Septin 2 (SEPT2) (AA 287-336) antibodySEPT2 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬, Pig, 斑马鱼, Bat, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Septin 2 (SEPT2) antibodySEPT2 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Septin 2 (SEPT2)
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别名
- SEPT2
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背景
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Description: Filament-forming cytoskeletal GTPase. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri.
Gene: 2-Sep
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分子量
- 41 kDa
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基因ID
- 4735
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UniProt
- Q15019
抗原
-
