Casein Kinase 1 delta 抗体 (Internal Region)
Quick Overview for Casein Kinase 1 delta 抗体 (Internal Region) (ABIN6257097)
抗原
See all Casein Kinase 1 delta (CSNK1D) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Casein Kinase 1 delta Antibody detects endogenous levels of total Casein Kinase 1 delta.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Casein Kinase 1 delta, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Casein Kinase 1, delta (CSNK1D) (AA 152-398), (Isoform delta) antibody
CSNK1D 适用: 人 WB, ELISA, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (AA 301-415) antibodyCSNK1D 适用: 人 WB, ELISA, IF, IHC (p), PLA 宿主: 小鼠 Monoclonal 4H8 unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (Internal Region) antibodyVerified CSNK1D 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Casein Kinase 1, delta (CSNK1D) antibodyCSNK1D 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (AA 301-415) antibodyCSNK1D 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (AA 1-409) antibodyCSNK1D 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (AA 1-409) antibodyCSNK1D 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (Internal Region) antibodyCSNK1D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (AA 143-192) antibodyCSNK1D 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 猴, 小鸡, 豚鼠, 斑马鱼, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Casein Kinase 1, delta (CSNK1D) (AA 250-350) antibodyCSNK1D 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Casein Kinase 1 delta (CSNK1D) (Casein Kinase 1, delta (CSNK1D))
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别名
- CSNK1D
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背景
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Description: Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Phosphorylates connexin-43/GJA1, MAP1A, SNAPIN, MAPT/TAU, TOP2A, DCK, HIF1A, EIF6, p53/TP53, DVL2, DVL3, ESR1, AIB1/NCOA3, DNMT1, PKD2, YAP1, PER1 and PER2. Central component of the circadian clock. In balance with PP1, determines the circadian period length through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. YAP1 phosphorylation promotes its SCF(beta-TRCP) E3 ubiquitin ligase-mediated ubiquitination and subsequent degradation. DNMT1 phosphorylation reduces its DNA-binding activity. Phosphorylation of ESR1 and AIB1/NCOA3 stimulates their activity and coactivation. Phosphorylation of DVL2 and DVL3 regulates WNT3A signaling pathway that controls neurite outgrowth. EIF6 phosphorylation promotes its nuclear export. Triggers down-regulation of dopamine receptors in the forebrain. Activates DCK in vitro by phosphorylation. TOP2A phosphorylation favors DNA cleavable complex formation. May regulate the formation of the mitotic spindle apparatus in extravillous trophoblast. Modulates connexin-43/GJA1 gap junction assembly by phosphorylation. Probably involved in lymphocyte physiology. Regulates fast synaptic transmission mediated by glutamate.
Gene: CSNK1D
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分子量
- 47 kDa
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基因ID
- 1453
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UniProt
- P48730
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途径
- Hedgehog Signaling, M Phase
抗原
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