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Ephrin B2 抗体 (pTyr330)

This anti-Ephrin B2 antibody is a 兔 多克隆 antibody detecting Ephrin B2 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6256709
发货至: 中国

Quick Overview for Ephrin B2 抗体 (pTyr330) (ABIN6256709)

抗原

See all Ephrin B2 (EFNB2) 抗体
Ephrin B2 (EFNB2)

适用

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人, 小鼠, 大鼠

宿主

  • 58
  • 4
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克隆类型

  • 50
  • 12
多克隆

标记

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This Ephrin B2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    pTyr330

    特异性

    Phospho-Ephrin B2 (Tyr330) Antibody detects endogenous levels of Ephrin B2 only when phosphorylated at Tyrosine 330.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Ephrin B2 around the phosphorylation site of Tyr330.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    Ephrin B2 (EFNB2)

    别名

    EFNB2

    背景

    Description: Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4. Together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation from EFNB2-expressing cells. May play a role in constraining the orientation of longitudinally projecting axons.

    Gene: EFNB2

    分子量

    37kDa

    基因ID

    1948

    UniProt

    P52799

    途径

    RTK signaling, Regulation of Muscle Cell Differentiation
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