CAMK2B 抗体 (pThr286)
Quick Overview for CAMK2B 抗体 (pThr286) (ABIN6256533)
抗原
See all CAMK2B 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pThr286
-
特异性
- Phospho-CaMK2 (Thr286) Antibody detects endogenous levels of CaMK2 only when phosphorylated at Threonine 286
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
免疫原
- A synthesized peptide derived from human CaMK2 around the phosphorylation site of Threonine 286
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
-
有效期
- 12 months
-
-
- CAMK2B (Calcium/calmodulin-Dependent Protein Kinase II beta (CAMK2B))
-
别名
- CaMK2
-
背景
-
Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Gene: CAMK2A
-
分子量
- 50kDa
-
基因ID
- 815
-
UniProt
- Q9UQM7, Q13557
-
途径
- WNT signaling, Interferon-gamma Pathway, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration, Regulation of long-term Neuronal Synaptic Plasticity
抗原
-