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MAPT 抗体 (pSer235)

This anti-MAPT antibody is a 兔 多克隆 antibody detecting MAPT in WB 和 ELISA. Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN6256205
发货至: 中国

Quick Overview for MAPT 抗体 (pSer235) (ABIN6256205)

抗原

See all MAPT 抗体
MAPT (Microtubule-Associated Protein tau (MAPT))

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This MAPT antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
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    pSer235

    特异性

    Phospho-Tau (Ser235) Antibody detects endogenous levels of Tau only when phosphorylated at Serine 235.

    预测反应

    Pig,Bovine,Horse,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Tau around the phosphorylation site of Ser235.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MAPT (Microtubule-Associated Protein tau (MAPT))

    别名

    MAPT

    背景

    Description: Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

    Gene: MAPT

    分子量

    78kDa

    基因ID

    4137

    UniProt

    P10636

    途径

    MAPK Pathway, Microtubule Dynamics, M Phase, Regulation of Cell Size
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