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ERBB3 抗体 (pTyr1289)

This anti-ERBB3 antibody is a 兔 多克隆 antibody detecting ERBB3 in WB, IHC, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6255799
发货至: 中国

Quick Overview for ERBB3 抗体 (pTyr1289) (ABIN6255799)

抗原

See all ERBB3 抗体
ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ERBB3 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
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    pTyr1289

    特异性

    Phospho-HER3/ErbB3 (Tyr1289) Antibody detects endogenous levels of ERBB3 only when phosphorylated at Tyr1289.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human ERBB3 around the phosphorylation site of Tyr1289.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))

    别名

    ERBB3

    背景

    Description: Tyrosine-protein kinase that plays an essential role as cell surface receptor for neuregulins. Binds to neuregulin-1 (NRG1) and is activated by it, ligand-binding increases phosphorylation on tyrosine residues and promotes its association with the p85 subunit of phosphatidylinositol 3-kinase (PubMed:20682778). May also be activated by CSPG5 (PubMed:15358134).

    Gene: ERBB3

    分子量

    185 kDa

    基因ID

    2065

    UniProt

    P21860

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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