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NRF2 抗体 (pSer40)

This anti-NRF2 antibody is a 兔 多克隆 antibody detecting NRF2 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6255303
发货至: 中国

Quick Overview for NRF2 抗体 (pSer40) (ABIN6255303)

抗原

See all NRF2 (NFE2L2) 抗体
NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 86
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多克隆

标记

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This NRF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    pSer40

    特异性

    Phospho-Nrf2 (Ser40) Antibody detects endogenous levels of Nrf2 only when phosphorylated at S40.

    预测反应

    Pig,Bovine,Horse,Rabbit,Dog,Chicken

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human nrf2 around the phosphorylation site of Ser40.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    NRF2 (NFE2L2) (Nuclear Factor (erythroid-Derived 2)-Like 2 (NFE2L2))

    别名

    NFE2L2

    背景

    Description: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

    Gene: NFE2L2

    分子量

    90 kDa

    基因ID

    4780

    UniProt

    Q16236

    途径

    ER-Nucleus Signaling, Negative Regulation of intrinsic apoptotic Signaling
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