FANCD2 抗体 (pSer222)
Quick Overview for FANCD2 抗体 (pSer222) (ABIN6255106)
抗原
See all FANCD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer222
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特异性
- Phospho-FANCD2 (Ser222) Antibody detects endogenous levels of FANCD2 only when phosphorylated at Serine 222.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human FANCD2 around the phosphorylation site of Ser222.
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亚型
- IgG
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anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibody
FANCD2 适用: 人, 小鼠 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-230) antibodyFANCD2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-291) antibodyFANCD2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 893-927) antibodyFANCD2 适用: 人 WB 宿主: 兔 Polyclonal RB49367 unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (Ser371) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 188-237), (pSer222) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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别名
- FANCD2
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背景
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Description: Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress. Required for the targeting, or stabilization, of BLM to non-centromeric abnormal structures induced by replicative stress. Promotes BRCA2/FANCD1 loading onto damaged chromatin. May also be involved in B-cell immunoglobulin isotype switching.
Gene: FANCD2
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分子量
- 166kDa
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基因ID
- 2177
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UniProt
- Q9BXW9
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途径
- DNA Damage Repair
抗原
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