Topoisomerase II alpha 抗体 (pSer1469)
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Quick Overview for Topoisomerase II alpha 抗体 (pSer1469) (ABIN6254985)
抗原
See all Topoisomerase II alpha (TOP2A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer1469
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特异性
- Phospho-Topoisomerase IIα (Ser1469) Antibody detects endogenous levels of Topoisomerase IIα.
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交叉反应
- 人, 小鼠
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纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
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免疫原
- A synthesized peptide derived from human Topoisomerase IIalpha around the phosphorylation site of Ser1469.
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亚型
- IgG
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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别名
- Topoisomerase IIalpha
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背景
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Description: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).
Gene: TOP2A
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分子量
- 190kDa
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基因ID
- 7153
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UniProt
- P11388
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases
抗原
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