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Topoisomerase II alpha 抗体 (pSer1469)

The 兔 多克隆 anti-Topoisomerase II alpha antibody is suitable to detect Topoisomerase II alpha in samples from 人 和 小鼠. It has been validated for WB 和 IHC.
产品编号 ABIN6254985
发货至: 中国
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Quick Overview for Topoisomerase II alpha 抗体 (pSer1469) (ABIN6254985)

抗原

See all Topoisomerase II alpha (TOP2A) 抗体
Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

适用

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人, 小鼠

宿主

  • 142
  • 52

克隆类型

  • 99
  • 95
多克隆

标记

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This Topoisomerase II alpha antibody is un-conjugated

应用范围

  • 134
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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    pSer1469

    特异性

    Phospho-Topoisomerase IIα (Ser1469) Antibody detects endogenous levels of Topoisomerase IIα.

    交叉反应

    人, 小鼠

    纯化方法

    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

    免疫原

    A synthesized peptide derived from human Topoisomerase IIalpha around the phosphorylation site of Ser1469.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

    别名

    Topoisomerase IIalpha

    背景

    Description: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).

    Gene: TOP2A

    分子量

    190kDa

    基因ID

    7153

    UniProt

    P11388

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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