CREB1 抗体 (pSer142)
Quick Overview for CREB1 抗体 (pSer142) (ABIN6254981)
抗原
See all CREB1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- pSer142
-
特异性
- Phospho-CREB (Ser142) Antibody detects endogenous levels of CREB only when phosphorylated at Serine 142.
-
预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
-
纯化方法
- The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
-
免疫原
- A synthesized peptide derived from human CREB around the phosphorylation site of Ser142.
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
-
CREB1 regulates glucose transport of glioma cell line U87 by targeting GLUT1." in: Molecular and cellular biochemistry, Vol. 436, Issue 1-2, pp. 79-86, (2018) (PubMed).
: "
-
CREB1 regulates glucose transport of glioma cell line U87 by targeting GLUT1." in: Molecular and cellular biochemistry, Vol. 436, Issue 1-2, pp. 79-86, (2018) (PubMed).
-
- CREB1 (cAMP Responsive Element Binding Protein 1 (CREB1))
-
别名
- CREB1
-
背景
-
Description: Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.
Gene: CREB1
-
分子量
- 43kDa
-
基因ID
- 1385
-
UniProt
- P16220
-
途径
- TLR signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Activation of Innate immune Response, Myometrial Relaxation and Contraction, Regulation of Cell Size, Toll-Like Receptors Cascades, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, Positive Regulation of fat Cell Differentiation
抗原
-