beta Catenin 抗体 (C-Term)
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Quick Overview for beta Catenin 抗体 (C-Term) (ABIN6254224)
抗原
See all beta Catenin (CATNB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-beta-Catenin
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序列
- MDPMMEHEMG GHHPGADYPV DGLPDLGHAQ DLMDGLPPGD SNQLAWFDTD L
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特异性
- Detects a band of approximately 95 kDa by Western blot in MNT1 and SH-SY5Y cell lysates.
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产品特性
- Catenin (cadherin-associated protein), beta 1, 88 kDa
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纯化方法
- Epitope affinity purified
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免疫原
- Purified recombinant peptide derived from within residues 731 aa to the C-terminus of human beta Catenin produced in E. coli.
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亚型
- IgG
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应用备注
- WB:1:500-1:2,000, IF:1:50-1:250, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
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限制
- 仅限研究用
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缓冲液
- PBS, 20 % glycerol and 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody solution should be gently mixed before use.
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储存条件
- 4 °C,-20 °C
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储存方法
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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: "Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation." in: Development (Cambridge, England), Vol. 144, Issue 8, pp. 1518-1530, (2017) (PubMed).
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: "Folate receptor 1 is necessary for neural plate cell apical constriction during Xenopus neural tube formation." in: Development (Cambridge, England), Vol. 144, Issue 8, pp. 1518-1530, (2017) (PubMed).
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- beta Catenin (CATNB) (Catenin, beta (CATNB))
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别名
- beta-Catenin
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背景
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Goat polyclonal antibody to Catenin (cadherin-associated protein), beta 1. Beta Catenin is a 88 kDa protein and is a key downstream effector in the Wnt signalling pathway. It is involved in early embryonic development and tumorigenesis. Beta Catenin is part of a complex of proteins that constitute adherens junctions, necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. This protein anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete.
cadherin-associated protein, CTNNB, CTNNB1, MRD19, armadillo antibody.
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分子量
- 88 kDa
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途径
- Peptide Hormone Metabolism
抗原
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