EGFR 抗体 (C-Term)
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Quick Overview for EGFR 抗体 (C-Term) (ABIN6254171)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- anti-ERBB1
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序列
- SHQISLDNPD YQQDFFPKEA KPNGIFKGST AENAEYLRVA PQSSEFIGA
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特异性
- This antibody gives a positive signal in the following human (HaCat, SKOV3 and H69) whole cell lysates by Western blot.
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产品特性
- Epidermal growth factor receptor
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纯化方法
- Epitope affinity purified
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免疫原
- Purified recombinant peptide derived from within residues 1,162 aa to the C-terminus of human ERBB1 produced in E. coli.
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亚型
- IgG
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应用备注
- WB:1:500-1:5,000, IHC-P:1:250-1:1,000, IHC-F:1:250-1:1,000
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限制
- 仅限研究用
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缓冲液
- PBS, 20 % glycerol and 0.05 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The antibody solution should be gently mixed before use.
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储存条件
- 4 °C,-20 °C
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储存方法
- For continuous use, store at 2-8 C for one-two days. For extended storage, store in -20 C freezer. Working dilution samples should be discarded if not used within 12 hours.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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别名
- ERBB1
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背景
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Goat polyclonal antibody to ERBB1. ERBB1 is a transmembrane glycoprotein that is a member of the protein kinase superfamily and a receptor for members of the epidermal growth factor family. It is a cell surface protein that binds to epidermal growth factor inducing receptor dimerization and tyrosine autophosphorylation and leading to cell proliferation. This receptor has been associated with cancer. Different protein isoforms encoded by multiple alternatively spliced transcript variants have been found for this gene.
EGFR, epidermal growth factor receptor, ERBB, HER1, mENA, NISBD2PIG61, antibody.
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
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